Caffeine Withdrawal Symptoms Onset of withdrawal symptoms can occur in as little as 6-12 hours after discontinuation and can last up to 9 days. The Top 10 Most Commonly Reported Caffeine Withdrawal Symptoms Are: in Public bookmarkswith caffeine_addictioncaffeine_withdrawalcaffeine_withdrawal_symptoms Note: Onset of withdrawal symptoms can occur in as little as 6-12 hours after discontinuation and can last up to 9 days. The Top 10 Most Commonly Reported Caffeine Withdrawal Symptoms Are: